Mathematical models are mainly used to depict real world problems that humans encounter in their daily explorations, investigations and activities. However, these mathematical models have some limitations as indeed the big challenges are the conversion of observations into mathematical formulations. If this conversion is inefficient, then mathematical models will provide some predictions with deficiencies. A specific real-world problem could then have more than one mathematical model, each model with its advantages and disadvantages. In the last months, the spread of covid-19 among humans have become fatal, destructive and have paralyzed activities across the globe. The lockdown regulations and many other measures have been put in place with the hope to stop the spread of this deathly disease that have taken several souls around the globe. Nevertheless, to predict the future behavior of the spread, humans rely on mathematical models and their simulations. While many models, have been suggested, it is important to point out that all of them have limitations therefore newer models can still be suggested. In this paper, we examine an alternative model depicting the spread behavior of covid-19 among humans. Different differential and integral operators are used to get different scenarios.The present paper describes a three compartment mathematical model to study the transmission of the current infection due to the novel coronavirus (2019-nCoV or COVID-19). We investigate the aforesaid dynamical model by using Atangana, Baleanu and Caputo (ABC) derivative with arbitrary order. We derive some existence results together with stability of Hyers-Ulam type. Further for numerical simulations, we use Adams-Bashforth (AB) method with fractional differentiation. The mentioned method is a powerful tool to investigate nonlinear problems for their respective simulation. Some discussion and future remarks are also given.The worldwide association of health (WHO) has stated that COVID-19 (the novel coronavirus disease-2019) as a pandemic. Here, the common SEIR model is generalized in order to show the dynamics of COVID-19 transmission taking into account the ABO blood group of the infected people. Fractional order Caputo derivative are used in the proposed model. Our study is guided by the results that have been obtained by Chen J, Fan H, Zhang L, et al. from three unique medical clinics in Wuhan and Shenzhen, China. In this study, the feasibility region of the proposed model are calculated plus the points of equilibrium. Also, the equilibrium points stability is examined. A unique solution existence for the proposed paradigm is proved via utilizing the fixed point theory with regards to Caputo fractional derivative. Numerical experiments of the proposed paradigm is done and we show its sensitivity to the fractional order.The present study aimed to compare a group of patients with obsessive-compulsive disorder (OCD; N = 270) before and during COVID-19 on specific obsessive-compulsive (OC) symptom dimensions and symptom severity. In addition, the study aimed to evaluate the associations of COVID-19-related stress responses with change in OC symptom dimensions and severity of symptoms as the result of the pandemic. Results showed that patients with OCD had higher scores on all OC symptom dimensions and symptom severity during the pandemic as compared to their scores from before the pandemic. Thus, the effect of COVID-19 is not limited to an increase in fears of contamination alone, but occurs across other symptom dimensions, including responsibility for harm, unacceptable thoughts, and symmetry. In addition, regression analyses indicated that COVID-19-related stress responses significantly predicted the observed increase in specific OC symptom dimensions and general severity, after controlling for pre-COVID-19 scores of symptoms and severity. The increase of symptoms as the result of COVID-19 might be best understood in the context of a non-specific stress-related response similar to the effects observed in non-clinical and other clinical populations.American Indian and Alaska Native (AI/AN) people are underrepresented in biomedical research, particularly in biospecimen research, yet little research has been conducted to assess AI/AN attitudes about biospecimen donation. Survey data were collected from 278 AI/AN people in Seattle, Washington in 2016 to assess general willingness to donate, background characteristics related to willingness, and circumstances that would increase or decrease willingness to donate biospecimens. Less than half (43%) of participants were willing to donate. General willingness was related to past donation, and trust in how researchers use and store biospecimens. However, willingness to donate for cancer research was 76%. Fear of research exploitation and spiritual beliefs decreased willingness. Among those who were generally unwilling to donate, willingness increased if the biobank was run by a Native American organization, if the participant or family member had cancer and this was the disease being studied, if the community was involved in developing, reviewing, and approving the research, and if the expertise of researchers was known. Among those who were willing, willingness decreased if they had never heard of the research organization, and if the biobank was run by the federal government. Participation of AI/AN people in biobanking initiatives is critical to address health inequities and improve the health of AI/AN people, realize personalized medicine goals, and address the limited generalizability of current clinical and biospecimen research. These results highlight areas in which interventions could be developed to increase AI/AN donation of biospecimens for research with the ultimate goal of reducing health disparities.Despite the inverse relationship between physical activity (PA) and physical function, few older adults achieve PA recommendations. In response to observations that “lack of time” underlies reduced PA among older adults, recent work suggests even short bouts of PA can improve health and fitness. In addition, because they are frequently visited by older adults, an important conduit for PA promotion could be the primary care physician (PCP). However, most PCPs receive little training related to PA, rendering it difficult for them to offer meaningful counseling. RGDyK price Therefore, we explored the feasibility and impact of a PCP-prescribed one-minute daily functional exercise program, consisting of 30 s each of bodyweight push-ups and squats, among 24 patients 60 years of age or older. 42% of patients who were contacted started the exercise prescription and, over 24-weeks, completed approximately 114 sessions, while 75% completed at least half of the possible daily exercise sessions. As a group, the patients demonstrated increases in both maximal push-up and squat performance, though these increases plateaued following week-12.