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Conway Riggs posted an update 1 year, 5 months ago
Introduction Basal cell carcinoma (BCC) is a non-melanocytic skin malignancy arising from basal cells of epidermis or follicular structures. Etiology of BCC is a multifactorial combination of genotype, phenotype, and environmental factors. There are several clinical variants of BCC including nodular, cystic, superficial, morphoeic, keratotic, pigmented and micronodular. Aim The aim of our study was to analyze the recent clinical trends of basal cell carcinoma by reviewing a single institution’s experience. Methods Total number of 422 patients clinically diagnosed with basal cell carcinoma were included in the study. Data on age, gender, skin type, personal and family history, duration of disease, localization of lesions, clinical type of lesions, and recurrence rate were collected and analyzed. The data were statistically evaluated. Results More than 80% of all BCC’s were located on sun-exposed skin areas (p less then 0.05).The male /female ratio was 10.92. The nodular BCC was the most frequent type (59.2%), followed by the superficial (16.1%), pigmented (15.2%) and morphoeic (9.5%) types. The nodular and pigmented types were predominant located on the head and neck, whereas the trunk was the most common location for the superficial type (p less then 0.05). Selleck SIS17 The tumor is commonly found in concomitance with skin lesion related to chronic sun exposure, such as actinic keratoses, solar lentigines and facial telangiectasia. During this study period, 41 cases showed recurrence of the cancer as the overall recurrence rate was 9.7%. There were no cases with metastasis or fatal outcome. Conclusions The factors related to the development of BCC were older age and exposure to ultraviolet rays both in recreational and in occupational form. The prevention of BCC is based on the knowledge of risk factors, early diagnosis and treatment, particularly in susceptible populations. © 2019 Emina Kasumagic-Halilovic, Mediha Hasic, Nermina Ovcina-Kurtovic.Introduction Change in the fundus in myopic patients are often characterized by partially atrophic and tilted optic disc insertions. Due to the altered nerve fiber arrangement, it is more difficult to detect the initial pathological changes of the optic disc. This subject is important because myopia represents well known risk factor for glaucoma. Aim This study explored frequency of tilted optic disc in different degree of myopia which has major effect on glaucoma assesment due to unreliable OCTs parameters of the neuroretinal rim in patients with tilted disc. Methods Between September 2013 and December 2014, total number of 150 patiens from ophtalmic polyclinic “Dr Sefic” underwent complete ophtalmic examniation. Total of 300 eyes were tested. Patients were separated in 3 groups by diagnosis. Each group was divided by the size of the optic disc diameter into three categories. ANOVA test was used in analysis. Results Subjects with tilted disc shape have the highest degree of myopia, and there is a statistically significant difference with other forms of optic disc regardless of the size of the disc itself (p less then 0.05). The patients with a large disc (4.05 ± 0.65) had the highest degree of myopia in subclass of tilted discs, and these values decreased linearly in relation to the size of the tilted disc. Conclusion Myopia height values decreased linearly with respect to the size of the tilted disc. © 2019 Edita Dervisevic, Nejira Ibrisevic.Introduction DVD is a rare, poorly understood eye motility disorder of unknown etiology. In socially unacceptable deviation, surgical treatment is an option. We present patients operated with three different surgical methods. Aim To evaluate and compare different surgical approaches for treatment of dissociated vertical deviation (DVD). Methods Total amount of 20 patients with DVD of ≥ 20 PD are operated with three different techniques on superior rectus (SR) muscle Group I with preoperative angle of 20-30 PD was operated with 8 mm recession of SR, Group II with preoperative angle of ≥ 30 PD undergo 3 mm recession with posterior fixation on SR and Group III with preoperative angle of ≥ 30 PD undergo-splitting of SR muscle. Surgeries for associated horizontal deviations were performed before surgery for DVD. Follow up was three years. Results In all cases amount of DVD deviation was significantly reduced. No binocularity was gained. Although hyperdeviation of affected eye was reduced in all patients, we didn’t eliminate deviation completely. Despite smaller preoperative angle, residual angle was bigger (6-12 PD) in the patients in group I where only recession of SR was performed, compared to Group II and III where postoperative angle was 4-8 PD in both groups. Conclusion There are no recommended guidelines for the surgical treatment of DVD and treatment is based more on the surgeon’s experience than evidence based data. In our experience recession of the SR should be method of choice in the cases of smaller deviation. SR recession combined with posterior fixation suture and Y-splitting seems to be a safe and effective method for surgical treatment of unilateral DVD with bigger deviation angles. Y splitting with less surgical complications and increasing effect with time can be a good alternative to posterior fixation surgery. © 2019 Ivana Mravicic, Maja Pauk Gulic, Ante Barisic, Alma Biscevic, Melisa Ahmedbegovic Pjano, Ajla Pidro.Introduction Most important in the evaluation of thyroid thyroid disease is to differentiate a disease that is treated medically from a disease that requires surgical treatment. In preoperative differentiation of a malignant from a benign lesion are used different diagnostic methods (US, scintigraphy, FNAC, MRI). Aim The aim of the study was to determine the diagnostic value of fine needle aspiration cytology (FNAC) and serum thyroglobulin antibodies (TgAb) values in individual cytological categories. Methods The prospective study included 100 patients with scintigraphic cold thyroid nodules divided into two groups. The first group consisted of 50 patients with histopathological verified benign nodules and the second group of 50 patients with histopathological verified benign nodules. Demographic datas, FNAC findings, TgAb levels and final histopathological findings were recorded. FNAC with ultrasound (US) guidance was performed by the so-called Free hand technique. TgAtb values were estimated by the radio-immunity assay (RIA) method.

