Objective. To describe preceptor teaching challenges and preceptor development programming design preferences through a qualitative needs assessment. Methods. In 2018, 148 experiential education stakeholders across North Carolina (eg, preceptors, residency program directors, experiential faculty administrators, and practice site administrators) were invited to participate in 60-minute semi-structured interviews as part of a broad preceptor development needs assessment. Interview questions focused on (1) precepting challenges, (2) positive and negative features of preceptor development programs and, (3) preferences of program design. Interview transcripts were coded using thematic analysis. Results. Forty-two participants completed interviews, including preceptors from various rotation types, residency program directors, experiential faculty administrators, and institution administrators. Participants identified numerous teaching challenges related to learner, preceptor, and institutional levels. Example respocs and delivery formats, and sessions from educational and practice experts.Objective. Doctor of pharmacy programs are encouraged to incorporate research training in their curricula, but literature is lacking describing health system student research support. The purpose of this study is to evaluate a process supporting fourth-year student pharmacist research in a health system affiliated with a school of pharmacy.Methods. In 2017, clinical non-tenure track faculty transitioned from facilitating a fourth-year research elective to implementing a new student research process which matches students to research preceptors at the beginning of the academic year and provides training and resources throughout the year. This institutional review board approved pre-post study evaluated student pharmacist research participation, dissemination, and position placement at the time of graduation, comparing 3 years before to 3 years after new process implementation.Results. Thirty-three fourth-year students assigned to the health system graduated during 2015-2017, and 31 graduated 2018-2020. The percent of students who completed research projects increased significantly (48.5% vs 87.1%, p=.0013), the number of projects increased significantly (18 vs 35, p=.0047), presentations increased significantly (29 vs 63, p=.0001), and publications increased numerically (9 vs 16, p=.0699). Notably, the percent of research students who pursued postgraduate training increased (68.8% vs 96.3%), as well as the rate of placement into training programs (81.8% vs 92.3%); for non-research students, the percent who pursued training also increased (17.6% vs 75%), but the rate of placement remained the same (66.7%).Conclusion. The new fourth-year pharmacy student research process supported increased research productivity.Objective. This study sought to evaluate faculty/preceptor and student perceptions regarding preferences and timeliness of communication on professionalism and value.Methods. An anonymous questionnaire was sent to faculty/preceptors and students evaluating preferred method of communication, response time expectations, impact on professionalism, and perception of being valued. The University of Mississippi Institutional Review Board granted expedited approval.Results. A total of 253/924 responses were received (27% response rate). Responses came from 27 (11%) full-time faculty, 94 (37%) preceptors, and 132 (52%) students. Overall, email was the preferred communication method for non-time sensitive information (98%) with a majority of faculty/preceptors and students indicating 48hrs was a reasonable response time. Participants largely felt less then 24 hours to be a reasonable response time for text or phone call communication. Most students indicated response time to be somewhat or not impactful (58%) on their view of professionalism, while faculty and preceptors indicated response time to be neutral or somewhat impactful (60%). The majority of students (77%) felt that the response time from faculty/preceptors impacted their perceptions of feeling valued and important.Conclusion. Communication preferences among faculty/preceptors and students differ. Professionalism related to communication is important for all groups, and timeliness in communication between faculty, preceptors, and students impacts perception of value and self-worth.

Degarelix is associated with high rates of injection site reaction. The US Food and Drug Administration approved relugolix, an oral gonadotropin-releasing hormone (GnRH) antagonist, for the treatment of advanced prostate cancer patients.

This systematic review and network meta-analysis aimed to compare the efficacy and safety of relugolix versus degarelix.

A systematic search was performed using major web databases for studies published before January 30, 2021, according to the Preferred Reporting Items for Systematic Review and Meta-analyses (PRISMA) extension statement for a network meta-analysis. Studies that compared the efficacy (12-mo castration rate with testosterone ≤50 ng/dl) and safety (adverse events [AEs]) of relugolix or degarelix and of the control group (GnRH agonists) were included. Bromelain We used the Bayesian approach in the network meta-analysis.

Four studies (n = 2059) met our eligibility criteria. The main efficacy analysis was conducted for two different treatments (relugolix and all dose efficacy and safety of relugolix are comparable with those of degarelix, albeit with no injection site reaction. Such data should be interpreted with caution until large-scale direct comparison studies with a longer follow-up are available.

We found that relugolix, an oral gonadotropin-releasing hormone (GnRH) antagonist, has comparable efficacy and safety with degarelix, a parenteral GnRH antagonist, for the treatment of advanced prostate cancer patients.

We found that relugolix, an oral gonadotropin-releasing hormone (GnRH) antagonist, has comparable efficacy and safety with degarelix, a parenteral GnRH antagonist, for the treatment of advanced prostate cancer patients.

Analyse the relationship between the sociodemographic profile of the DIADA study participants and the rate of compliance with the follow-up assessments in the early stage of this project’s intervention for depression and unhealthy alcohol use offered within primary care.

A non-experimental quantitative analysis was conducted. The sociodemographic data of DIADA [Detección y Atención Integral de Depresión y Abuso de Alcohol en Atención Primaria (Detection and Integrated Care for Depression and Alcohol Use in Primary Care)] study participants had been previously collected. At the time of the evaluation (September 12, 2019), only the participants who had been in the project for a minimum of 3 months were included. By using univariate (Chi-squared) analyses, we studied the association between participants’ sociodemographic profile and their rate of compliance with the first follow-up assessment at 3 months after study initiation.

At the date of the evaluation, 584 adult participants were identified, of which 389 had been involved in the project for more than 3 months.