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	<title>Recash test site | Loft McDonough | Activity</title>
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				<title>Loft McDonough posted an update: A series of five benzimidazole-based compounds were [&#133;]</title>
				<link>https://recash.wpsoul.net/activity/p/57837/</link>
				<pubDate>Thu, 12 Dec 2024 08:12:46 +0000</pubDate>

									<content:encoded><![CDATA[<p>A series of five benzimidazole-based compounds were identified using a machine learning algorithm as potential inhibitors of the respiratory syncytial virus (RSV) fusion protein. These compounds were synthesized, and compound 2 in particular exhibited excellent in vitro potency with an EC50 value of 5 nM. This new scaffold was then further refined&hellip;<span class="activity-read-more" id="activity-read-more-57837"><a href="https://recash.wpsoul.net/activity/p/57837/" rel="nofollow ugc">[Read more]</a></span></p>
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				<title>Loft McDonough posted an update: 23&#160;±&#160;176.53&#160;ng/ml; TNF-α 57.53&#160;±&#160;3.87&#160;pg/ml), while ma [&#133;]</title>
				<link>https://recash.wpsoul.net/activity/p/50896/</link>
				<pubDate>Wed, 11 Dec 2024 14:16:15 +0000</pubDate>

									<content:encoded><![CDATA[<p>23&nbsp;±&nbsp;176.53&nbsp;ng/ml; TNF-α 57.53&nbsp;±&nbsp;3.87&nbsp;pg/ml), while markedly been suppressed in the treatment group (AS-L IgE 1100.25&nbsp;±&nbsp;135.32&nbsp;ng/ml; TNF-α 38.47&nbsp;±&nbsp;3.26&nbsp;pg/ml; AS-H IgE 459.46&nbsp;±&nbsp;74.75&nbsp;ng/ml; TNF-α 24.38&nbsp;±&nbsp;3.85&nbsp;pg/ml). Among Th17 cell-related factors, DNCB treatment increased mRNA expression of IL-6, IL-17, IL-23, STAT3, and ROR-γt, but reduced T&hellip;<span class="activity-read-more" id="activity-read-more-50896"><a href="https://recash.wpsoul.net/activity/p/50896/" rel="nofollow ugc">[Read more]</a></span></p>
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				<title>Loft McDonough became a registered member</title>
				<link>https://recash.wpsoul.net/activity/p/50815/</link>
				<pubDate>Wed, 11 Dec 2024 14:06:49 +0000</pubDate>

				
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