Extensive bursectomy of the subacromial bursa may not be recommended in rotator cuff repair surgery, though future in vivo human studies are needed to confirm these observations. Level of evidence Basic Science Study; Biomechanics and Histology.Background Pain management approaches during uterine aspiration vary, with methods including local anesthetic, oral analgesics, moderate sedation, deep sedation, or a combination of approaches. For local anesthetic approaches specifically, we continue to have suboptimal pain control [1]. Gabapentin as an adjunct to pain management has proven to be beneficial in gynecological surgery. We sought to evaluate the impact of gabapentin on perioperative pain during surgical management of first trimester abortion or early pregnancy loss with uterine aspiration under local anesthesia. Objectives We hypothesized that adding gabapentin to local anesthesia will reduce perioperative and postoperative pain associated with uterine aspiration. Secondary outcomes included tolerability of gabapentin, and postoperative pain, nausea, vomiting, and anxiety. Study design We conducted a randomized double-blinded placebo-controlled trial of gabapentin 600 mg given 1-2 hours pre-operatively among subjects receiving a 1st trimester utignificant changes in pain score preoperatively or intraoperatively. Subjects who received gabapentin had significantly lower levels of pain at 10 minutes post surgery [mean difference (SE) = -13.0(-5.0), p-value = 0.01] and 30 minutes post surgery [-10.8(-5.1), p=0.03] compared to subjects who received placebo. Median nausea scores and incidence of emesis pre- and postoperatively did not differ between groups. Similarly, anxiety scores did not differ between groups, pre- or post-procedure. At 10 and 30 minutes post-procedure, most participants reported no or mild side effects and this did not differ between groups. Conclusion Preoperative gabapentin did not reduce pain during uterine aspiration. However, it did reduce postoperative pain, which may prove to be a desired attribute of its use, particularly in cases where postoperative pain may be a greater challenge.Objective This study investigated factors related to the satisfaction level of cochlear implants for the elderly. Methods A survey was conducted by sending an anonymous self-reported questionnaire to medical facilities specializing in cochlear implantation throughout Japan and members of cochlear implant self-help groups aged 65 years and older. C-176 The subjects were divided into two age-based groups (under 75 and 75 years and older) to analyze the usage of cochlear implants. Binary logistic regression was performed to analyze factors related to the satisfaction level of the recipients with hearing improvements provided by cochlear implants (p less then 0.05). Results Responses were received from 60 cochlear implant users. The mean age of the respondents was 74.9±6.87 (mean ± 1SD) years. The mean cochlear implant use was 12.4 ± 4.0 (mean ± 1SD) hours per day. Regarding satisfaction with the cochlear implants, 93.3% responded “somewhat satisfactory” or better, indicating at least moderate satisfaction. However, fel in providing valuable rehabilitation for elderly patients with cochlear implants.Objectives This study aims to evaluate the application of the University of Pennsylvania Smell Identification Test (UPSIT) in Thailand, as well as to conduct an odor detection threshold test using phenyl ethyl alcohol and a 30-odor smell identification test. Methods This study was conducted from May 2019 to March 2020. We included healthy volunteers without any olfactory complaints. All participants underwent the UPSIT, an evaluation of odor detection threshold, and a 30-odor smell identification test. Results One hundred fifty participants were included in our study. The overall mean score on the UPSIT was 26.04 ± 6.59 points and ranged from 9 to 39.7. For participants aged under 60 years, the mean UPSIT score was 29.08 ± 4.67 points, while the mean score of those 60 years of age and over was 19.20 ± 4.97 points (mean difference of 9.88 points), a difference that was statistically significant (95% CI 8.23 to 11.53, p less then 0.0001). The mean lowest log value on the odor detection threshold test was -7.12 ± 1.64. This was -7.53 ± 1.05 in participants under 60 years of age and -6.20 ± 2.27 in those 60 years of age and over (mean difference of 1.33; 95% CI 0.80 to 1.86, p less then 0.0001). Items in the 30-odor smell identification test with correct response rates greater than 70% included fish sauce, banana, coffee, patchouli water, coconut, lemongrass, orange, ammonia, vinegar, tea leaf, Thai perfume, jasmine, pandan, curry, lime, durian, cola, corn, pineapple, strawberry, and grape. Conclusions This study identified the odor detection threshold, UPSIT scores, and suitable odors to use in smell identification in a Thai population.Synchronized and coherent activity in resting-networks during normal brain functioning could be altered in disconnection syndrome like schizophrenia. Study of neural oscillations as assessed by EEG appears to be a promising proposition to understand the pathophysiology of schizophrenia in patients and their first-degree relatives, where disturbances in neural oscillations point towards genetic predisposition. Therefore, present study aims at establishing EEG based biomarkers for early detection and management strategies. Thirty-two patients with schizophrenia, 28 first-degree relatives and 31 healthy controls (HC) participated in the study. Resting brain activity was recorded using 128-channel electroencephalography. After pre-processing and independent component analysis (ICA), an equivalent current dipole was estimated for each IC. Total of 1551 independent and localizable EEG components across all groups were used in subsequent analysis. Power spectral density and source coherence between IC clusters were computed. Patients and first-degree relatives displayed significantly higher power spectral density (PSD) than HC for all frequency bands in left parahippocampal gyrus (PHG) (-7, -26, 8; BA 27). Another region within left deep PHG (-4, -28, 1), however, distinguished patients from first-degree relatives and HC in terms of significantly lower PSD in higher frequency bands. Functional connectivity (FC) was found to be lower in patients and higher in relatives compared to HC between different resting-state network areas. In patients, connectivity was lower compared to first-degree relatives. Altered activity within left PHG and FC of primarily this with other areas in resting-state network can serve as state and trait markers of schizophrenia.