1 kg d-1. H2, located near an industrial zone, had a total mass flux of 33.7 kg d-1 and contributed to the most Ni, Cr, Pb, Zn, and Hg fluxes. This study indicates that the water quality improvements observed are still not enough to meet the regulations. Stricter enforcement is required as well as further investigation to identify any illegal pollution sources.Crustacean shell waste disposal is considered as biggest problem in seafood processing centers. Incineration and landfilling are the commonest ways of disposal of the waste which causes environmental pollution. Microbial bio-conversion is one of the promising approaches to minimize the wastes by utilizing the same for deriving different value added metabolites. In this perspective, chitinase- and protease-producing bacterial strains were isolated from shrimp culture pond, and the potent isolate was subsequently identified as Alcaligenes faecalis SK10. Fermentative optimization of the production of chitinase (85.42 U/ml), protease (58.57 U/ml), and their catalytic products, viz., N-acetylamino sugar (84 μg/ml) and free amino acids (112 μg/ml), were carried out by utilizing shrimp and crab shell powder as principal substrate. The fermented hydrolysate (FH) was subsequently applied to evaluate its potential to be a candidate fertilizer for the growth of leguminous plant Pisum sativum and Cicer arietinum, and thesate of waste crustacean shell as biofertilizer.Type 2 diabetes (T2D) is one of the most widely spread metabolic disorder also called as “life style” disease. Due to the alarming number of patients, there is great need to therapies targeting functions which can help in maintaining the homeostasis of glucose levels and improving insulin sensitivity. Detailed analysis was done through various research and review papers which was searched using MEDLINE, BIOSIS, and EMBASE using various keywords. This search retrieved the most appropriate content on these molecules targeting UPP pathway. From this extensive review involving UPP pathway, it was concluded that the role of ubiquitin’s is not only limited to neurodegenerative disorders but also plays a critical role in progression of diabetes including obesity, insulin resistance, and various neurogenerative disorders but it also targets proteasomal degradation including mediation of cellular signaling pathways. Thus, drugs targeting UPP not only may show effect against diabetes but also are therapeutically beneficial in the treatment of diabetes-associated complications which may be obtained. Thus, based on the available information and data on UPP functions, it can be concluded that regulation of UPP pathway via downstream regulators mainly E1, E2, and E3 may bring promising results. Drugs targeting these transcriptional factors may emerge as a novel therapy in the treatment of diabetes and diabetes-associated complications.Gaseous formaldehyde present indoors is often in low-medium concentration, as compared to that contained in manufactured products, but still poses great threat to human health. Thus, this work aims to fabricate Ce-Eu/TiO2 hollow microspheres, which showed excellent photocatalytic performance toward formaldehyde. Furthermore, photocatalytical degradation performance of Ce-Eu/TiO2 hollow microspheres toward formaldehyde was investigated. The kinetics of degradation mechanism of gaseous formaldehyde for different concentrations and different temperatures vs time were studied, and the simulation and experimental results were also compared. It was found that formaldehyde concentration had an effect on the degradation process, which was consistent with different kinetics reactions. HS-10296 chemical structure At low concentration, the degradation rate was decided by the adsorption rate, and no accumulation of adsorbent occurred. This process was consistent with the first-order kinetics law, which was established by L-H dynamics theory and Arrhenius equation. At medium concentration, the degradation process of formaldehyde was controlled by both adsorption and photocatalysis, which was consistent with the power law model. The 3D model of formaldehyde degradation process by Ce-Eu/TiO2 hollow microspheres at different concentrations vs time was established, and the results showed that the simulation equations were in good agreement with the experimental results.Nowadays, the emissions from the diesel engines are focused lot to minimise the environmental pollutions in accordance with the emission standards. In this regard, biodiesels are found to be efficient for the diesel engines due to their higher energy contents and low exhaust emissions. Use of biofuel in association with diesel will be an efficient way for the cost-effective performance of the diesel engines with reduced pollutions. The COME is an efficient combustible oil, in which the diesel is blended at different proportions to identify their suitability in the diesel engines. In this regard, the properties of the COME-Diesel blends are determined and analysed for their influence on the combustion characteristics. To understand the performance and emission characteristics of blends, experiments are carried out on the variable compression ratio (VCR) engine keeping the blend, compression ratio, load, and speed as variables. The response surface methodology (RSM) used as a tool for designing and conducting the experiments according to the predetermined variables. The experimental sets generated are performed to determine the NO and HC emissions (response functions). The adequacy of the models is verified through ANOVA and through the p and F tests. The experimental design matrix is also used in training the artificial neural network (ANN) to develop the empirical models. The models from RSM and ANN are experimented and the results obtained from both the models are compared for their accuracy levels. Once the hypothesis is developed for the biodiesel and engine setup, the emission models will be used for the optimising the engine operating parameters and blends to minimise the pollutions from engine for wide operating conditions.Composition of groundwater in the mining areas can be affected by oxidation of sulfide minerals and related reactions. Given that in the Miduk copper mine area, groundwater is the only available water resource for drinking and agriculture purposes. In the study area, assessment and measurement of groundwater physicochemical properties such as pH, TDS, EC, major cations, and major anions were performed. Physicochemical studies showed that the calcium and sulfate are the main cations and anions (Ca-SO4 water type), respectively. Groundwater in the area is mainly fresh and with a source of meteoric water infiltration. Three pollution indices, HEI, HPI, and Cd, were selected to evaluate the concentration level of ten of heavy metal(loid)s (Al, As, Cd, Cu, Fe, Mn, Mo, Ni, Pb, and Zn). To investigate the source and relations between heavy metal(loid)s, multivariate statistical analysis was executed for eleven variables. The results of pollution indices showed that samples in group 1 (mine pit area) have the highest level of pollution and considering that the samples of this group are in the closest distance to the mine pit and group 3 (springs) around the study area had the least level of pollution.