In addition, overexpression of human AR produced no benefit to disease onset and progression in SOD1G93A mice. In conclusion, the disease course of SOD1G93A mice is independent of AR expression levels, implicating other mechanisms involved in mediating the sex differences in ALS. Our findings using Nestin-Cre mice, which show an inherent metabolic…[Read more]

Still, what really sets these membranes apart is their natural long term (up to 60 days) stability at extreme acidic (pH 0) and alkaline conditions (pH 14) and a relevant monovalent selectivity of up to 6.3 for Cl- over SO42-. Overall this work showcases PDADMA/PSS based saloplastics as highly promising and stable anion-exchange membranes, that…[Read more]

Furthermore, combined with the proposed occlusion algorithm, the model can predict the important amino acids of proteins that are crucial for binding, thus providing a biological interpretation.

As per the 2017 WHO fact sheet, Coronary Artery Disease (CAD) is the primary cause of death in the world, and accounts for 31% of total fatalities.…[Read more]

1 kg d-1. H2, located near an industrial zone, had a total mass flux of 33.7 kg d-1 and contributed to the most Ni, Cr, Pb, Zn, and Hg fluxes. This study indicates that the water quality improvements observed are still not enough to meet the regulations. Stricter enforcement is required as well as further investigation to identify any illegal…[Read more]