A contract prepared by the institution and signed by the supervisor and the student could help specify the task and may serve as a starting point. In case of a conflict, grievance mechanisms also need to be clear and explicit. Supervisors ought to assist the career development of the students and guide them to become independent researchers. sellec…[Read more]

Hypoxia in a solid tumor microenvironment (TME) can lead to the overexpression of hypoxia-inducible factor-1α (HIF-1α), which correlates to tumor metastasis. Reactive oxygen species (ROS) induced tumor cell apoptosis is becoming a promising method in tumor treatment. Currently, the ROS generating systems, e.g., photodynamic treatment and s…[Read more]

Aortic levels of nitrate/nitrite ratio were significantly elevated. Acetylcholine-induced relaxation was impaired as the E

decreased significantly in aortae. Moreover, a significant increase was seen in the level of aortic intima/media ratio. Canagliflozin treatment significantly improved vascular function, lipid profile and inflammation and…[Read more]