014). The mutation rate of driver gene Ephrin-A2 (

) was significantly reduced after radiotherapy (Fisher’s exact test, P=0.035). However, comparison between the pre- and post-radiotherapy groups reveals no significant differences in other content.

Our study revealed the overall genomic profile of ESCC before and after radiotherapy and…[Read more]

Morquio syndrome is caused by the deficiency of N-acetylgalactosamine-6-sulfate sulfatase (GALNS) enzyme, which is required for the catabolism of glycosaminoglycans (namely, chondroitin-6-sulfate and keratan sulfate). Pathogenic accumulation of these glycosaminoglycans occurs throughout the body. The various organs and tissues affected are bones,…[Read more]