Metformin treatment compromised most of the gut microbiota changes and metabolic improvements linked to prebiotic intervention. The prebiotic modulated specific bacteria, associated with the improvement of anthropometry (i.e. a decrease in Desulfovibrio and Clostridium sensu stricto). A large increase in Bifidobacterium appears as a signature of…[Read more]

AA, OR =2.346, 95% CI 1.127-4.884) and the recessive model (GG vs. AG + AA, OR =1.503, 95% CI 1.049-2.152). Further sensitivity analysis indicated that the frequency of G allele and GG genotype in NSCL/P children was significantly higher than those in the control. However, there was no significant statistical differences after Bonferroni…[Read more]

Given the increasing levels of air pollution, understanding the direct shielding response of the skin to air pollutants as a whole under exclusion of the influence from the inside of body is important. We applied topically the water soluble ambient air pollutants to the mouse skin and observed the histological response using 0.3 mM of H2SO3 as a…[Read more]