Aging was associated with decreased number (Spearman r = - 0.598, P  less then  0.0001, n = 56), decreased ACE2 (r = - 0.677, P  less then  0.0004), and increased ACE activity (r = 0.872, P  less then  0.0001) (n = 23) in HSPCs. Migration or proliferation of LSK cells in basal or in response to stromal-derived factor-1α in old cells is attenuate…[Read more]