Congenital infections refer to a group of perinatal infections that may have similar clinical presentations, including rash and ocular findings. TORCH is the acronym that covers these infections (toxoplasmosis, other [syphilis], rubella, cytomegalovirus, herpes simplex virus). There are, however, other important causes of intrauterine/perinatal…[Read more]

Hydrogen/deuterium exchange (HDX) is used in protein biophysics to probe folding dynamics, intermolecular interactions, epitope and other mapping [1, 2]. A typical procedure often involves HDX in buffered D2O solution followed by pepsin digestion, and liquid chromatography/electrospray ionization Mass Spectrometry (LC-ESI-MS) analysis. In this…[Read more]

The designation of noninvasive lobular neoplasia applies to atypical epithelial proliferations composed of noncohesive cells secondary to loss or functional alteration of E-cadherin-mediated cell adhesion. The morphologic spectrum of noninvasive lobular neoplasia encompasses atypical lobular hyperplasia (ALH) and classic lobular carcinoma in situ…[Read more]

iods. In sensitivity analyses, the significant benefit of EVAR in the perioperative period and that of OSR in the mid-term period were not changed. No funnel plot asymmetry was identified in all analyses. CONCLUSIONS Compared to OSR, EVAR associated with lower perioperative mortality and higher mortality in the mid-term period for intact…[Read more]