iods. In sensitivity analyses, the significant benefit of EVAR in the perioperative period and that of OSR in the mid-term period were not changed. No funnel plot asymmetry was identified in all analyses. CONCLUSIONS Compared to OSR, EVAR associated with lower perioperative mortality and higher mortality in the mid-term period for intact infrarenal AAA. The superiority of EVAR was absent in the early-term period, and the inferiority of EVAR in the mid-term period disappeared in the long-term and very long-term periods. OBJECTIVES YouTube videos have become a common resource for trainees to learn about surgical procedures. Carotid endarterectomy (CEA) is one example procedure that may be performed by multiple specialties and with a variety of techniques. Little is known about educational content and the representation of vascular surgeons in these videos. We sought to compare the educational quality of CEA YouTube videos, techniques demonstrated, and prevalence of each specialty. METHODS YouTube was programmatically searched for the terms “carotid endarterectomy,” “carotid endarterectomy surgery,” “carotid endarterectomy technique,” “carotid endarterectomy CEA,” and “carotid artery surgery.” Videos that met inclusion criteria were analyzed for surgical technique, procedural steps, surgeon specialty, video length, and date. Videos were determined to have high-quality educational content if the video included English language captions or narration and demonstrated key steps of the procedure division of the common facial vein, ideos were older than videos by cardiac surgeons (6.0 ± 1.1 y vs. 3.0 ± 0.5 y, p less then 0.05) and neurosurgeons (6.0 ± 1.1 y vs. 3.1 ± 0.8 y, p less then 0.05). CONCLUSIONS Despite more views, the field of vascular surgery is underrepresented in YouTube videos demonstrating carotid endarterectomy. Vascular surgery videos tend to be older and make up a minority of high-quality videos. As more learners turn to YouTube for information about surgical procedures, vascular surgeons should expand their online presence through the production and collection of high-quality videos for trainees. OBJECTIVE Patients with peripheral arterial occlusive disease (PAOD) have a poor prognosis and a high prevalence of comorbidity. This study investigated whether sarcopenia and/or myosteatosis negatively affect long-term survival in patients with PAOD. GF120918 in vivo METHODS This was a single-center retrospective cohort study of 686 consecutive patients diagnosed and treated for PAOD and who underwent computed tomography scanning. Cross-sectional muscle measurements were obtained at the level of the third lumbar vertebra. Optimal stratification was used to define sex-specific and body mass index (BMI)-specific cutoff values for sarcopenia and myosteatosis, respectively. The Cox proportional hazards model was used to determine the effect of sarcopenia and myosteatosis on overall survival. RESULTS Sarcopenia was associated with age, BMI, myosteatosis, malignancy, congestive heart failure, hemodialysis, and Fontaine 4 classification. Myosteatosis was associated with age, sarcopenia, type 2 diabetes mellitus, hypertension, chronic obstructive pulmonary disease, malignancy, congestive heart failure, ischemic stroke, and Fontaine 4 classification. Sarcopenia (hazard rate [HR], 2.82; 95% confidence interval [CI], 2.05-3.86; p less then 0.001) and myosteatosis (HR, 4.13; 95% CI, 3.03-5.63; p less then 0.001) were both associated with reduced survival in univariable analysis. When adjusted for other prognostic markers, myosteatosis (HR, 2.09; 95% CI, 1.46-2.99; p less then 0.001) was still associated with reduced overall survival in the multivariable model but sarcopenia (HR, 1.40; 95% CI, 0.97-2.01; p = 0.073) was not. CONCLUSIONS Muscle depletion is independently associated with a poorer overall survival in patients with PAOD. Myosteatosis is a stronger predictor than sarcopenia, which indicates that quality is more important than quantity. Results should be interpreted with caution due to missing data on medication usage. OBJECTIVES The U.S. Preventative Services Task Force guidelines for abdominal aortic aneurysm (AAA) screening are based mainly on studies of older Caucasian males from non-U.S. POPULATIONS This study was designed to analyze the findings of a large, all-inclusive AAA screening program in the U.S. METHODS Screening events were held nationally by a U.S. non-profit organization between 2001 and 2017. AAA screening was offered regardless of risk profile. Participants filled out a demographics form with known co-morbidities. Significant risk factors were determined using logistic regression with backward stepwise variable selection. Odds ratios (OR) reported with 95% confidence intervals. RESULTS A total of 9,457 screened participants (47% male) were analyzed. The mean age was 67 ±9 with 40.8% between 65 and 75 years old. Most participants were Caucasian (83.4%), followed by African American (13.1%). Screened risk factors included hypertension (58.1%), hyperlipidemia (54.9%), smoking (52.0%), cardiac disease (29.2%(OR, 1.69; 1.61-2.46), and current smokers (OR, 6.33; 2.62-15.24 for females and OR, 2.50; 1.70-3.65 for males). CONCLUSIONS This study shows that there remain high-risk groups outside the current guidelines which would likely benefit from AAA screening. Risk factors for AAA include male gender, smoking, cardiac disease, family history of AAA and increasing age. The most significant risk factor is current smoking status. This pilot study examined whether a combined aerobic resistance exercise program reduced fatigue and the potential inflammatory and epigenetic mechanisms in patients with head and neck cancer (HNC) receiving intensity-modulated radiotherapy. The exercise group (N = 12) received a 3-month supervised aerobic resistance exercise intervention that was initiated before a 6-week radiotherapy regimen; the control group (N = 14) received standard care. Fatigue was measured using Multidimensional Fatigue Inventory-20; physical function measures included a 6-minute walk distance (6MWD), chair stands, bicep curls, and hand grip strength. Inflammatory markers and DNA methylation data were acquired using standardized protocol. Patients were mostly white (93%) and male (81%) with a mean age of 57 years. At the end of the intervention, the exercise group had a marginal decrease in fatigue compared with the control (-5.0 vs. 4.9; P = 0.10). The exercise group had a significantly greater improvement in 6MWD (29.8 vs. -55.5 m; P = 0.