Mitochondrial function has long been the focus of many therapeutic strategies for ameliorating age-related neurodegeneration and cognitive decline. Historically, the role of mitochondria in non-neuronal cell types has been overshadowed by neuronal mitochondria, which are responsible for the bulk of oxidative metabolism in the brain. Despite this…[Read more]

The certification module is a lightweight neural network based on statistical learning ideas and a multi-source feature fusion mechanism. The information entropy of the iris feature label was used to set the iris entropy feature category label and design certification module functions according to the category label to obtain the certification…[Read more]

CONCLUSION Our study shows that lineage-specific DNA methylation signatures are stably maintained during regeneration, and regeneration enhancers are preset as hypomethylated before injury. In contrast, chromatin accessibility is dynamically changed during regeneration. Many enhancers driving regeneration gene expression as well as upstream…[Read more]