Moreover, the addition of poly (ADP-ribose) polymerase inhibitors further potentiates the K+CS antitumor effect. K+CS represents a new class of therapy for multiple types of blood cancers and will stimulate future investigations to exploit DNA-damage repair and nucleocytoplasmic transport for cancer therapy in general.γ-Glutamyl carboxylase…[Read more]

Advanced prostate cancer preferential metastasis to bone is associated with osteomimicry. MINDIN is a secreted matrix protein upregulated in prostate tumors that overexpresses bone-related genes during prostate cancer progression. Na+/H+ exchanger regulatory factor (NHERF-1) is a scaffold protein that has been involved both in tumor regulation and…[Read more]

According to the will of the German legislator, community-based housing communities are supposed to help implement the pluralistic welfare in mixed care settings and strategies in the structure of long-term care. They follow the principle of shared responsibility, which is characterized by the co-productive cooperation of professionals, working…[Read more]