Health care systems frequently have to decide whether to implement interventions designed to reduce gaps in the quality of care. A lack of information on the cost of these interventions is often cited as a barrier to implementation. In this article, we describe methods for estimating the cost of implementing a complex intervention. We review…[Read more]

BACKGROUND Esophageal carcinoma is a malignant gastrointestinal tumor with a very poor prognosis. MicroRNA (miR)-1304 is a newly discovered non-coding RNA, which shows differential expression in other cancers, and its clinical value in esophageal carcinoma remains unclear. AIM To explore the expression of miR-1304 in patients with esophageal…[Read more]

Cardiopulmonary bypass (CPB) is required during most cardiac surgeries. CBP drives systemic inflammation and multiorgan dysfunction that is especially severe in neonatal patients. Limited understanding of molecular mechanisms underlying CPB-associated inflammation presents a significant barrier to improve clinical outcomes. To better understand…[Read more]

Previous studies have shown that non-SMC condensin I complex subunit G (

) overexpression is correlated to poor prognosis of multiple cancer types. Herein, we explored the underlying mechanism of

-mediated cardia adenocarcinoma (CA) proliferation and cell cycle regulation.

The protein profiling technology was used to analyze the…[Read more]