In animal study, 4 weeks treadmill exercise upregulated claudin-1 (p less then 0.05) and occludin (p less then 0.01) protein expression level in 21 months old mice. Also, zonula occluden-1 (ZO-1) protein expression level was not significant difference among all mice group. In addition, old mice group had higher level of serum LPS compared to young…[Read more]