No marked depletion of mtDNA nor mitochondrial mass was caused by the splicing variant. However, defects that the impaired capacity of OXPHOS, reduced ATP generation, increased ROS and decreased membrane potential were observed in the mutant cells, which promoted a ubiquitin-binding mitophagy instead of apoptosis. Conclusions The novel splicing…[Read more]

This review examines the body of evidence behind Wolbachia’s negative effect on eggs, assesses nutritional parasitism as a key cause and considers how these impacts could be overcome to achieve efficient large-scale rearing of these mosquitoes.In recent years, substantial efforts have been made to dissect the composition of microbial communities…[Read more]

Quarantine has been associated with increased rates of suicide, anger, acute stress disorder, depression and post-traumatic stress disorder, with symptoms continuing even years after quarantine ends. There are several predisposing risk factors including the inhabited environment, unique aspects of assessment as well as phenomena seen specifically…[Read more]